Defective TH17 development in human neonatal T cells involves reduced RORC2 mRNA content

J Allergy Clin Immunol. 2013 Sep;132(3):754-756.e3. doi: 10.1016/j.jaci.2013.04.014. Epub 2013 May 29.

Authors

Sytze de Roock¹, Arie J Stoppelenburg², Rianne Scholman², Sanne B E A Hoeks², Jenny Meerding², Berent J Prakken², Marianne Boes²

Affiliations

¹ Department of Pediatric Immunology, Center for Molecular and Cellular Intervention CMCI, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address: [email protected].
² Department of Pediatric Immunology, Center for Molecular and Cellular Intervention CMCI, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.

PMID: 23726039
DOI: 10.1016/j.jaci.2013.04.014

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Cytokines / genetics
Cytokines / immunology
Fetal Blood / cytology
Fetal Blood / immunology
Forkhead Transcription Factors / immunology
Humans
Infant, Newborn
Nuclear Receptor Subfamily 1, Group F, Member 3 / genetics*
Nuclear Receptor Subfamily 1, Group F, Member 3 / immunology
RNA, Messenger / metabolism
T-Lymphocytes, Regulatory / immunology*
Th17 Cells / immunology*
Young Adult

Substances

Cytokines
FOXP3 protein, human
Forkhead Transcription Factors
Nuclear Receptor Subfamily 1, Group F, Member 3
RNA, Messenger
RORC protein, human