Two Cases of Diffuse Large B-Cell Lymphomas in the Cervical Lymph Nodes in Patients with Low-Grade Gastric Marginal Zone B-Cell Lymphoma (MALT Lymphoma)

Clin Endosc. 2013 May;46(3):288-92. doi: 10.5946/ce.2013.46.3.288. Epub 2013 May 31.

Abstract

It is well known that gastric mucosa-associated lymphoid tissue (MALT) lymphomas are associated with Helicobacter pylori infection and have a good prognosis. However, although rare, these low-grade lymphomas transform to the high-grade diffuse large B-cell lymphomas (DLBCLs) which are thought to be the important cause of death in patients with MALT lymphoma. We report two cases of DLBCLs in the cervical lymph nodes that occurred 10 years and 1.5 years after diagnosing low-grade gastric MALT lymphomas.

Keywords: Helicobacter pylori; Lymphoma, B-cell, marginal zone; Lymphoma, large B-cell, diffuse; Stomach neoplasms.