Mechanosensitivity in the upper extremity following breast cancer treatment

J Hand Ther. 2014 Jan-Mar;27(1):4-11. doi: 10.1016/j.jht.2013.08.021. Epub 2013 Sep 29.

Abstract

Study design: Descriptive, cross-sectional.

Introduction: Breast cancer (BC) treatments place the nervous system at risk, which may contribute to upper extremity (UE) mechanosensitivity.

Purpose of the study: To evaluate elbow extension range of motion (EE-ROM) during upper limb neurodynamic testing (ULNT) post-BC treatment.

Methods: ULNT EE-ROM was measured for 145 women post-BC treatment. Women were sub-grouped by presence/absence of pain and lymphedema.

Results: Mean EE-ROM during ULNT1 was -22.3° (SD 11.9°) on the unaffected limb and -25.99° (SD 13.1°) on the affected limb. The women with pain and lymphedema had the greatest limitation in EE-ROM during ULNT1 testing, particularly of their affected limb (-33.8°, SD 12.9). Symptoms were reported more frequently in the affected chest, shoulder, arm, elbow, and hand. The intensity of symptoms was greater at the affected chest (p = 0.046), shoulder (p = 0.033) and arm (p = 0.039).

Conclusions: Women with lymphedema and pain after BC treatment may present with altered neural mechanosensitivity.

Level of evidence: 3a.

Keywords: Breast cancer; Lymphedema; Neurodynamics.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analysis of Variance
  • Arthrometry, Articular
  • Body Mass Index
  • Breast Neoplasms / physiopathology*
  • Breast Neoplasms / therapy
  • Cross-Sectional Studies
  • Elbow Joint / physiopathology
  • Female
  • Humans
  • Lymph Node Excision
  • Lymphedema / physiopathology*
  • Middle Aged
  • Movement / physiology
  • Neurologic Examination*
  • Pain / physiopathology*
  • Pain Measurement
  • Postoperative Complications / physiopathology
  • Range of Motion, Articular / physiology
  • Retrospective Studies
  • Sentinel Lymph Node Biopsy
  • Shoulder Joint / physiopathology
  • Upper Extremity / physiopathology*