Coupling between DNA replication and cell division mediated by the FtsA protein in Escherichia coli: a pathway independent of the SOS response, the "TER" pathway

J Bacteriol. 1985 Nov;164(2):950-3. doi: 10.1128/jb.164.2.950-953.1985.

Abstract

Inhibition of DNA synthesis prevented the recovery of cell division in filaments of D-3R [ftsA3(Ts) recA56] returned to the permissive temperature. The FtsA protein may be a signal involved in the "TER" pathway, a series of events that coordinate cell division with DNA replication, that is independent of the SOS pathway.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / biosynthesis
  • Bacterial Proteins / genetics
  • Bacterial Proteins / physiology*
  • Cell Division
  • DNA Replication* / drug effects
  • DNA, Bacterial / biosynthesis
  • Escherichia coli / cytology
  • Escherichia coli / genetics
  • Escherichia coli / physiology*
  • Genes, Bacterial
  • Hydroxyurea / pharmacology
  • Mutation
  • Nalidixic Acid / pharmacology
  • RNA, Bacterial / biosynthesis
  • Temperature

Substances

  • Bacterial Proteins
  • DNA, Bacterial
  • RNA, Bacterial
  • Nalidixic Acid
  • Hydroxyurea