"Green" functionalization of magnetic nanoparticles via tea polyphenol for magnetic resonance/fluorescent dual-imaging

Nanoscale. 2014;6(3):1305-10. doi: 10.1039/c3nr05003c.

Abstract

Tea polyphenol serves as an environmentally friendly ligand-exchange molecule to synthesize multifunctional metal-doped superparamagnetic iron oxide nanoparticles via a catechol-metal coordination interaction. The resultant particles not only exhibit excellent hydrophilicity and protein adsorption resistance, but also are applicable as magnetic resonance/fluorescent dual-imaging probes due to their high T₂ relaxivity, autofluorescence and large cellular uptake.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adsorption
  • Biocompatible Materials / chemistry
  • Contrast Media / chemistry
  • Ferric Compounds / chemistry
  • Green Chemistry Technology*
  • HeLa Cells
  • Humans
  • Ligands
  • Magnetic Resonance Imaging
  • Magnetic Resonance Spectroscopy
  • Metal Nanoparticles / chemistry
  • Metals / chemistry
  • Microscopy, Fluorescence
  • Nanoparticles / chemistry*
  • Nanotechnology / methods*
  • Optics and Photonics
  • Polyphenols / chemistry*
  • Spectroscopy, Fourier Transform Infrared
  • Tea / chemistry*

Substances

  • Biocompatible Materials
  • Contrast Media
  • Ferric Compounds
  • Ligands
  • Metals
  • Polyphenols
  • Tea
  • ferric oxide