Cerebellar Symptoms Are Associated With Omission Errors and Variability of Response Time in Children With ADHD

J Atten Disord. 2017 Feb;21(3):190-199. doi: 10.1177/1087054713517745. Epub 2016 Jul 27.

Abstract

Objective: We examined the presence of cerebellar symptoms in ADHD and their association with behavioral markers of this disorder.

Method: Sixty-two children with ADHD and 62 typically developing (TD) children were examined for cerebellar symptoms using the ataxia rating scale and tested using Conners' Continuous Performance Test.

Results: Children with ADHD had significantly more cerebellar symptoms compared with the TD children. Cerebellar symptom scores decreased with age in the ADHD group; in the TD group remained stable. In both groups, cerebellar symptoms were associated with parent-rated hyperactive/impulsive symptoms, variability of response time standard error (RT-SE) and increase of RT-SE as the test progresses. More variables were associated with cerebellar symptoms in the ADHD group including omission errors, overall RT-SE and its increase for prolonged interstimulus intervals.

Conclusion: Our results highlight the importance of research into motor functions in children with ADHD and indicate a role for cerebellar impairment in this disorder.

Keywords: Conners’ Continuous Performance Test; attention-deficit/hyperactivity disorder; cerebellum; reaction time variability.

MeSH terms

  • Adolescent
  • Attention Deficit Disorder with Hyperactivity / physiopathology*
  • Brain Diseases / physiopathology*
  • Cerebellum / physiopathology*
  • Child
  • Female
  • Humans
  • Hyperkinesis / physiopathology
  • Impulsive Behavior / physiology
  • Male
  • Neuropsychological Tests
  • Psychomotor Disorders / physiopathology
  • Reaction Time / physiology
  • Sensorimotor Cortex / physiology