Decreased expression of the chromatin remodeler ATRX associates with melanoma progression

Zulekha A Qadeer; Sara Harcharik; David Valle-Garcia; Chen Chen; Miriam B Birge; Chiara Vardabasso; Luis F Duarte; Emily Bernstein

doi:10.1038/jid.2014.45

Decreased expression of the chromatin remodeler ATRX associates with melanoma progression

J Invest Dermatol. 2014 Jun;134(6):1768-1772. doi: 10.1038/jid.2014.45. Epub 2014 Jan 27.

Authors

Zulekha A Qadeer^#^{1

2

3}, Sara Harcharik^#^{1

2}, David Valle-Garcia^{1

2

4}, Chen Chen⁵, Miriam B Birge^{2

5}, Chiara Vardabasso^{1

2}, Luis F Duarte^{1

2

3}, Emily Bernstein^{1

2

3}

Affiliations

¹ Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, New York, NY 10029, USA.
² Department of Dermatology, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, New York, NY 10029, USA.
³ Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, New York, NY 10029, USA.
⁴ Institute for Cellular Physiology, Molecular Genetics Department, National Autonomous University of Mexico, Mexico City, Mexico.
⁵ Department of Pathology, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, New York, NY 10029, USA.

^# Contributed equally.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural

MeSH terms

Chromatin / chemistry*
Cohort Studies
DNA Helicases / metabolism*
DNA Methylation
Disease Progression
Female
Gene Expression Regulation, Neoplastic*
Humans
Male
Melanoma / metabolism*
Melanoma / pathology
Mutation
Neoplasm Metastasis
Nevus / metabolism
Nuclear Proteins / metabolism*
Protein Structure, Tertiary
Skin Neoplasms / metabolism*
Skin Neoplasms / pathology
X-linked Nuclear Protein

Substances

Chromatin
Nuclear Proteins
DNA Helicases
ATRX protein, human
X-linked Nuclear Protein

Publication types

MeSH terms

Substances

Grants and funding