Objective: To investigate the association between cigarette smoking and ischemic stroke.
Methods: A case-control study was conducted. Investigators got the available information from the cases and controls by questionnaires. Logistic regression models were used to analyze the relationship between smoking and ischemic stroke in this study.
Results: A total number of 1037 cases and 1205 controls were included in this study. As the results showed, cigarette smoking was associated with ischemic stroke (OR = 1.368, 95% CI 1.158-1.616). After adjustment for age, body mass index, waist hip ratio, blood pressure, blood glucose, blood lipid, stroke family history and alcohol, the relationship between smoking and ischemic stroke was still significant (OR =2. 158, 95% CI 1.293-3.600). And the more you smoke, the more you stroke. Compared with nonsmokers, the ORs of smokers with 1-9 / day, 10-19 / day and 20 - / day were 1.097, 1.168 and 2.950.
Conclusion: Cigarette smoking is a risk factor for ischemic stroke.