Desensitization protocol should not be used in acute lymphoblastic leukemia patients with silent inactivation of PEGasparaginase

Haematologica. 2014 Jul;99(7):e102-4. doi: 10.3324/haematol.2013.099663. Epub 2014 Mar 28.
No abstract available

Keywords: PEGasparaginase; acute lymphoblastic leukemia; desensitization protocol; silent inactivation.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies / immunology*
  • Asparaginase / administration & dosage
  • Asparaginase / immunology*
  • Desensitization, Immunologic*
  • Humans
  • Hypersensitivity / complications
  • Hypersensitivity / immunology*
  • Hypersensitivity / therapy*
  • Polyethylene Glycols / administration & dosage
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*

Substances

  • Antibodies
  • Polyethylene Glycols
  • pegaspargase
  • Asparaginase