Psychostimulant addiction treatment

Neuropharmacology. 2014 Dec:87:150-60. doi: 10.1016/j.neuropharm.2014.04.002. Epub 2014 Apr 12.

Abstract

Treatment of psychostimulant addiction has been a major, and not fully met, challenge. For opioid addiction, there is strong evidence for the effectiveness of several medications. For psychostimulants, there is no corresponding form of agonist maintenance that has met criteria for regulatory approval or generally accepted use. Stimulant-use disorders remain prevalent and can result in both short-term and long-term adverse consequences. The mainstay of treatment remains behavioral interventions. In this paper, we discuss those interventions and some promising candidates in the search for pharmacological interventions. This article is part of the Special Issue entitled 'CNS Stimulants'.

Keywords: Addiction; Psychostimulant; Treatment.

Publication types

  • Review

MeSH terms

  • Central Nervous System Stimulants / administration & dosage*
  • Central Nervous System Stimulants / pharmacokinetics
  • Humans
  • Randomized Controlled Trials as Topic
  • Self Administration
  • Substance Withdrawal Syndrome / physiopathology
  • Substance Withdrawal Syndrome / therapy
  • Substance-Related Disorders / physiopathology
  • Substance-Related Disorders / therapy*

Substances

  • Central Nervous System Stimulants