Epidemiology of heart failure with preserved ejection fraction

Heart Fail Clin. 2014 Jul;10(3):377-88. doi: 10.1016/j.hfc.2014.04.003.

Abstract

Heart failure with preserved ejection fraction (HFPEF) is a common condition, and the prevalence is projected to increase further. Studies differ in the reported incidence and mortality associated with this condition, although there is agreement that between a third and one-half of all patients with heart failure have HFPEF. Although several consensus statements and guidelines have been published, some recent randomized clinical trials have reported low mortality, raising doubts about whether all patients diagnosed with HFPEF have HFPEF or whether the condition is heterogeneous in its cause and prognosis. The overall reported prognosis of patients with HFPEF remains poor.

Keywords: Epidemiology; Heart failure; Mortality; Preserved ejection fraction; Prognosis.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aged
  • Cause of Death*
  • Female
  • Heart Failure / diagnosis*
  • Heart Failure / epidemiology*
  • Heart Failure / therapy
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Prognosis
  • Reference Values
  • Risk Assessment
  • Stroke Volume / physiology*
  • Survival Analysis
  • Syndrome