Abstract
The susceptibility of common marmosets and cotton-top tamarins to infection by HIV-2 in vivo was tested. One year and 19 months, respectively, post-inoculation, sera taken from three of four animals from each species are reactive for HIV-2 antibodies and HIV-specific nucleotide sequences were demonstrated in short-term cultures of PBL from two cotton-top tamarins. The animals remain in good health.
MeSH terms
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Acquired Immunodeficiency Syndrome / microbiology*
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Animals
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Aotus trivirgatus / microbiology*
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Blotting, Southern
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Blotting, Western
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Callithrix / microbiology*
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Callitrichinae / microbiology*
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Cebidae / microbiology*
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DNA, Viral / analysis
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Disease Models, Animal
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Enzyme-Linked Immunosorbent Assay
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HIV Antibodies / analysis
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HIV-1 / genetics
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HIV-1 / immunology
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HIV-1 / pathogenicity*
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HIV-2 / genetics
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HIV-2 / immunology
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HIV-2 / pathogenicity*
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Nucleic Acid Hybridization
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Saguinus / microbiology*
Substances
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DNA, Viral
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HIV Antibodies