Immobilization of captive tigers (Panthera tigris) with a combination of tiletamine, zolazepam, and detomidine

Zoo Biol. 2015 Jan-Feb;34(1):40-5. doi: 10.1002/zoo.21157. Epub 2014 Aug 18.

Abstract

The aims of this study were to evaluate the effects of the administration of a combination of tiletamine-zolazepam and detomidine (TZD) in 9 tigers (Panthera tigris). Nine captive tigers were immobilized with tiletamine-zolazepam and detomidine administered intramuscularly. At the end of the procedure immobilization was partially reversed with atipamezole. Lateral recumbency was achieved in 15.6 ± 5.9 min. The median induction score [scored 1 (excellent) to 4 (poor)] was 1. The immobilization score [scored 1 (poor) to 6 (too deep)] was 5 (4-5) at all study times. After atipamezole administration, all tigers experienced severe ataxia and incoordination. Median recovery score [scored 1 (excellent) to 4 (poor)] was 2.5 (range 2-3). No neurologic and/or important adverse reactions were noticed within 5 days after recovery. The combination tiletamine-zolazepam with detomidine proved to be effective in immobilizing captive healthy tigers but it maybe associated with hypertension and ataxia during recovery. Zoo Biol. 34:40-45, 2015. © 2014 Wiley Periodicals Inc.

Keywords: Panthera tigris; atipamezole; detomidine; immobilization; telazol.

Publication types

  • Clinical Trial

MeSH terms

  • Anesthetics, Combined / pharmacology*
  • Anesthetics, Dissociative / pharmacology*
  • Animals
  • Animals, Zoo*
  • Female
  • Hypnotics and Sedatives / pharmacology*
  • Imidazoles
  • Immobilization / methods
  • Immobilization / veterinary*
  • Male
  • Tigers / physiology*
  • Tiletamine
  • Zolazepam

Substances

  • Anesthetics, Combined
  • Anesthetics, Dissociative
  • Hypnotics and Sedatives
  • Imidazoles
  • Tiletamine
  • detomidine
  • Zolazepam