Implantation of the new Nit-Occlud PDA-R device in children below 10 kilogram

Catheter Cardiovasc Interv. 2015 Jun;85(7):1203-8. doi: 10.1002/ccd.25688. Epub 2015 Mar 24.

Abstract

Background: Interventional closure of patent ductus arteriosus (PDA) has become a common and safe procedure in most pediatric cath labs. Interventional treatment of PDAs still remains a challenge in those children with low body weight and a large PDA. The Nit-Occlud PDA-R® device was developed and especially designed for large PDAs. We report our most recent experience in children with a body weight lower than 10 kg.

Materials and methods: The PDA-R® device was used in seven children (age 1-10, median 6 months) with a body weight from 4.1 to 9.7 kg (median 5.9 kg): ductal length was 12 mm (median), with a large ampulla (median 9 mm) which exceeded the diameter of the aorta (median 6 mm) and large diameter (median minimal diameter 4 mm). In six cases, the Nit-Occlud PDA-R was selected with an aortic disc of 12 mm and in one case an occluder with an aortic disc of 14 mm.

Results: Occlusion of the PDA was documented by angiography and/or echocardiography in all cases. At a mean follow-up of 21.4 months, no flow obstruction to the left or right pulmonary artery or new onset coarctation of the aorta was noted.

Conclusions: The Nit-Occlud PDA-R® device is suitable in children with a body weight below 10 kg when a relative large PDA is present.

Keywords: coil/device/transcatheter; embolization; interventional devices/innovation; pediatric intervention.

MeSH terms

  • Age Factors
  • Body Weight*
  • Cardiac Catheterization / adverse effects
  • Cardiac Catheterization / instrumentation*
  • Coronary Angiography
  • Coronary Circulation
  • Ductus Arteriosus, Patent / diagnosis
  • Ductus Arteriosus, Patent / physiopathology
  • Ductus Arteriosus, Patent / therapy*
  • Echocardiography, Doppler, Color
  • Female
  • Hemodynamics
  • Humans
  • Infant
  • Male
  • Patient Selection
  • Prosthesis Design
  • Pulmonary Circulation
  • Retrospective Studies
  • Risk Factors
  • Septal Occluder Device*
  • Treatment Outcome