Abstract
We describe the serum immunoglobulin A (IgA) antibody response to Norwalk virus infection in human volunteers and compare it with previously described IgM and total antibody responses. Whereas specific IgA and IgM peak within 2 weeks after onset of symptoms, titers of total blocking antibody continue to rise, implying mediation by IgG antibody.
MeSH terms
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Antibodies, Viral / analysis
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Antibodies, Viral / biosynthesis
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Binding, Competitive
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Gastroenteritis / immunology*
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Humans
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Immunoassay
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Immunoglobulin A / analysis
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Immunoglobulin A / biosynthesis*
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Immunoglobulin G / analysis
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Immunoglobulin M / analysis
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Immunoglobulin M / biosynthesis
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Kinetics
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Norwalk virus / immunology*
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Virus Diseases / immunology*
Substances
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Antibodies, Viral
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Immunoglobulin A
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Immunoglobulin G
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Immunoglobulin M