Clinical characteristics and course of patients with diabetes entering cardiac rehabilitation

Diabetes Res Clin Pract. 2015 Feb;107(2):267-72. doi: 10.1016/j.diabres.2014.11.006. Epub 2014 Dec 3.

Abstract

Background: Using data from the Italian SurveY on carDiac rEhabilitation (ISYDE-2008), this study provides insight into the level of implementation of Cardiac Rehabilitation (CR) in patients with diabetes.

Methods: Data from 165 CR units were collected online from January 28th to February 10th, 2008.

Results: The study cohort consisted of 2281 patients (66.9 ± 12 yrs); 475 (69.7 ± 10 yrs, 74% male) patients with diabetes and 1806 (66.2 ± 12 yrs, 72% male) non-diabetic patients. Compared to non-diabetic patients, patients with diabetes were older and showed more comorbidity [myocardial infarction (32% vs. 19%, p < 0.0001), peripheral artery disease (10% vs. 5%, p < 0.0001), chronic obstructive pulmonary disease (20% vs. 11%, p < 0.0001), chronic kidney disease (20% vs. 6%, p < 0.0001), and cognitive impairment (5% vs. 2%, p = 0.0009), respectively], and complications during CR [re-infarction (3% vs. 1%, p = 0.04), acute renal failure (9% vs. 4%, p < 0.0001), sternal revision (3% vs. 1%, p = 0.01), inotropic support/mechanical assistance (7% vs. 4%, p = 0.01), respectively]; a more complex clinical course and interventions with less functional evaluation and a different pattern of drug therapy at hospital discharge. Notably, in 51 (3%) and in 104 (6%) of the non-diabetic cohort, insulin and hypoglycemic agents were prescribed, respectively, at hospital discharge from CR suggesting a careful evaluation of the glycemic metabolism during CR program, independent of the diagnosis at the admission. Mortality was similar among diabetic compared to non-diabetic patients (1% vs. 0.5%, p = 0.23).

Conclusions: This survey provided a detailed overview of the clinical characteristics, complexity and more severe clinical course of diabetic patients admitted to CR.

Keywords: Cardiac rehabilitation; Cardiopulmonary exercise testing; Chronic heart failure; Diabetes; Exercise training; Myocardial infarction.

Publication types

  • Multicenter Study
  • Observational Study

MeSH terms

  • Aged
  • Blood Glucose / metabolism
  • Cardiac Rehabilitation*
  • Cardiovascular Diseases / epidemiology*
  • Cohort Studies
  • Comorbidity
  • Data Collection
  • Diabetes Mellitus, Type 1 / complications*
  • Diabetes Mellitus, Type 1 / diagnosis
  • Diabetes Mellitus, Type 1 / epidemiology*
  • Diabetes Mellitus, Type 2 / complications*
  • Diabetes Mellitus, Type 2 / diagnosis
  • Diabetes Mellitus, Type 2 / epidemiology*
  • Disease Progression*
  • Female
  • Hospitalization / statistics & numerical data
  • Humans
  • Italy / epidemiology
  • Male
  • Middle Aged
  • Patient Discharge / statistics & numerical data
  • Prevalence
  • Prognosis
  • Prospective Studies
  • Risk Factors

Substances

  • Blood Glucose