Drosophila melanogaster show a threshold effect in response to radiation

Dose Response. 2014 May 5;12(4):551-81. doi: 10.2203/dose-response.13-047.Antosh. eCollection 2014 Dec.

Abstract

We investigate the biological effects of radiation using adult Drosophila melanogaster as a model organism, focusing on gene expression and lifespan analysis to determine the effect of different radiation doses. Our results support a threshold effect in response to radiation: no effect on lifespan and no permanent effect on gene expression is seen at incident radiation levels below 100 J/kg. We also find that it is more appropriate to compare radiation effects in flies using the absorbed energy rather than incident radiation levels.

Keywords: Drosophila melanogaster; gene expression; low dose radiation; threshold effect.