'I was thinking too much': experiences of HIV-positive adults with common mental disorders and poor adherence to antiretroviral therapy in Zimbabwe

Trop Med Int Health. 2015 Jul;20(7):903-13. doi: 10.1111/tmi.12502. Epub 2015 Mar 23.

Abstract

Objective: To document the lived experiences of people with both poor mental health and suboptimal adherence to antiretroviral therapy in high HIV prevalence settings.

Methods: In-depth qualitative interviews were conducted with 47 (female = 31) HIV-positive adults who scored above the cut-point on a locally validated scale for common mental disorders (CMDs). Purposive sampling was used to recruit participants with evidence of poor adherence. Six additional key informant interviews (female = 6) were conducted with healthcare workers. Data were collected and analysed inductively by an interdisciplinary coding team.

Results: The major challenges faced by participants were stressors (poverty, stigma, marital problems) and symptoms of CMDs ('thinking too much', changes to appetite and sleep, 'burdened heart' and low energy levels). Thinking too much, which appears closely related to rumination, was the symptom with the greatest negative impact on adherence to antiretroviral therapy among HIV-positive adults with CMDs. In turn, thinking too much was commonly triggered by the stressors faced by people living with HIV/AIDS, especially poverty. Finally, participants desired private counselling, access to income-generating activities and family engagement in mental health care.

Conclusions: Better understanding of the local expression of mental disorders and of underlying stressors can inform the development of culturally sensitive interventions to reduce CMDs and poor adherence to antiretroviral therapy.

Keywords: HIV/AIDS; VIH/SIDA; adherence; adherencia; adhésion; antiretroviral therapy; barreras; barriers; barrières; compliance; depresión; depression; dépression; mental health; salud mental; santé mentale; terapia antirretroviral; thérapie antirétrovirale.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications
  • Adult
  • Anti-HIV Agents / therapeutic use*
  • Culture
  • Female
  • HIV Infections / complications*
  • HIV Infections / drug therapy
  • HIV Infections / psychology
  • Health Services Needs and Demand
  • Humans
  • Interviews as Topic
  • Male
  • Medication Adherence*
  • Mental Disorders / complications*
  • Middle Aged
  • Poverty
  • Prevalence
  • Social Stigma
  • Social Support
  • Spouses
  • Stress, Psychological* / etiology
  • Thinking
  • Simbabwe

Substances

  • Anti-HIV Agents