Molecular blood group typing in Banjar, Jawa, Mandailing and Kelantan Malays in Peninsular Malaysia

Rahayu Abd Gani; Siti Mariam Manaf; Zainuddin Zafarina; Sundararajulu Panneerchelvam; Geoffrey Keith Chambers; Mohd Noor Norazmi; Hisham Atan Edinur

doi:10.1016/j.transci.2015.03.009

Molecular blood group typing in Banjar, Jawa, Mandailing and Kelantan Malays in Peninsular Malaysia

Transfus Apher Sci. 2015 Aug;53(1):69-73. doi: 10.1016/j.transci.2015.03.009. Epub 2015 Mar 16.

Authors

Rahayu Abd Gani¹, Siti Mariam Manaf², Zainuddin Zafarina³, Sundararajulu Panneerchelvam², Geoffrey Keith Chambers⁴, Mohd Noor Norazmi⁵, Hisham Atan Edinur⁶

Affiliations

¹ Royal Malaysia Police Forensic Laboratory, Selangor, Malaysia; Human Identification Unit, School of Health Sciences, Health Campus, Universiti Sains Malaysia, Kelantan, Malaysia.
² Human Identification Unit, School of Health Sciences, Health Campus, Universiti Sains Malaysia, Kelantan, Malaysia.
³ Human Identification Unit, School of Health Sciences, Health Campus, Universiti Sains Malaysia, Kelantan, Malaysia; Malaysian Institute of Pharmaceutical and Nutraceuticals (IPharm), Ministry of Science, Technology and Innovation (MOSTI), Penang, Malaysia.
⁴ School of Biological Sciences, Victoria University of Wellington, New Zealand.
⁵ Human Identification Unit, School of Health Sciences, Health Campus, Universiti Sains Malaysia, Kelantan, Malaysia; Institute for Research in Molecular Medicine (INFORMM), School of Health Sciences, Health Campus, Universiti Sains Malaysia, Kelantan, Malaysia.
⁶ Human Identification Unit, School of Health Sciences, Health Campus, Universiti Sains Malaysia, Kelantan, Malaysia. Electronic address: [email protected].

PMID: 25819336
DOI: 10.1016/j.transci.2015.03.009

Abstract

In this study we genotyped ABO, Rhesus, Kell, Kidd and Duffy blood group loci in DNA samples from 120 unrelated individuals representing four Malay subethnic groups living in Peninsular Malaysia (Banjar: n = 30, Jawa: n = 30, Mandailing: n = 30 and Kelantan: n = 30). Analyses were performed using commercial polymerase chain reaction-sequence specific primer (PCR-SSP) typing kits (BAG Health Care GmbH, Lich, Germany). Overall, the present study has successfully compiled blood group datasets for the four Malay subethnic groups and used the datasets for studying ancestry and health.

Keywords: Blood groups; Malay sub-ethnic groups; Phenotype frequencies.

Publication types

Clinical Trial
Research Support, Non-U.S. Gov't

MeSH terms

Blood Group Antigens / genetics*
Blood Grouping and Crossmatching*
Databases, Nucleic Acid*
Ethnicity / genetics*
Female
Genetic Loci*
Humans
Malaysia / ethnology
Male

Substances

Blood Group Antigens