A database of age-appropriate average MRI templates

Neuroimage. 2016 Jan 1;124(Pt B):1254-1259. doi: 10.1016/j.neuroimage.2015.04.055. Epub 2015 May 2.

Abstract

This article summarizes a life-span neurodevelopmental MRI database. The study of neurostructural development or neurofunctional development has been hampered by the lack of age-appropriate MRI reference volumes. This causes misspecification of segmented data, irregular registrations, and the absence of appropriate stereotaxic volumes. We have created the "Neurodevelopmental MRI Database" that provides age-specific reference data from 2 weeks through 89 years of age. The data are presented in fine-grained ages (e.g., 3 months intervals through 1 year; 6 months intervals through 19.5 years; 5 year intervals from 20 through 89 years). The base component of the database at each age is an age-specific average MRI template. The average MRI templates are accompanied by segmented partial volume estimates for segmenting priors, and a common stereotaxic atlas for infant, pediatric, and adult participants. The database is available online (http://jerlab.psych.sc.edu/NeurodevelopmentalMRIDatabase/).

Keywords: Average MRI templates; Brain development; Lifespan MRI; Neurodevelopmental MRI Database.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Aging / physiology*
  • Brain / anatomy & histology*
  • Brain / growth & development*
  • Child
  • Child, Preschool
  • Databases, Factual*
  • Female
  • Humans
  • Image Processing, Computer-Assisted / standards*
  • Infant
  • Infant, Newborn
  • Information Dissemination
  • Internet
  • Magnetic Resonance Imaging / methods*
  • Magnetic Resonance Imaging / statistics & numerical data*
  • Male
  • Middle Aged
  • Reference Values
  • Stereotaxic Techniques
  • Young Adult