Progression of blood pressure and cardiovascular outcomes in hypertensive patients in a reference center

Arq Bras Cardiol. 2015 Apr;104(4):292-8. doi: 10.5935/abc.20150001. Epub 2015 Feb 3.
[Article in English, Portuguese]

Abstract

Background: Hypertension is a public health problem, considering its high prevalence, low control rate and cardiovascular complications.

Objective: Evaluate the control of blood pressure (BP) and cardiovascular outcomes in patients enrolled at the Reference Center for Hypertension and Diabetes, located in a medium-sized city in the Midwest Region of Brazil.

Methods: Population-based study comparing patients enrolled in the service at the time of their admission and after an average follow-up of five years. Participants were aged ≥ 18 years and were regularly monitored at the Center up to 6 months before data collection. We assessed demographic variables, BP, body mass index, risk factors, and cardiovascular outcomes.

Results: We studied 1,298 individuals, predominantly women (60.9%), and with mean age of 56.7 ± 13.1 years. Over time, there was a significant increase in physical inactivity, alcohol consumption, diabetes, dyslipidemia, and excessive weight. As for cardiovascular outcomes, we observed an increase in stroke and myocardial revascularization, and a lower frequency of chronic renal failure. During follow-up, there was significant improvement in the rate of BP control (from 29.6% to 39.6%; p = 0.001) and 72 deaths, 91.7% of which were due to cardiovascular diseases.

Conclusion: Despite considerable improvements in the rate of BP control during follow-up, risk factors worsened and cardiovascular outcomes increased.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Blood Pressure / physiology*
  • Body Mass Index
  • Brasilien
  • Cardiovascular Diseases / etiology
  • Cardiovascular Diseases / mortality*
  • Disease Progression
  • Female
  • Humans
  • Hypertension / complications
  • Hypertension / physiopathology*
  • Hypertension / therapy
  • Male
  • Middle Aged
  • Myocardial Infarction / epidemiology
  • Overweight / complications
  • Risk Factors
  • Sedentary Behavior
  • Stroke / epidemiology
  • Young Adult