Abstract
A spiropyran-based amphiphilic random copolymer was synthesized and self-assembled into photo-, pH-, and thermo-responsive micellar nanoparticles. The triple-stimuli triggered morphological changes of the nanoparticles were revealed by TEM and DLS. Highly efficient controlled release of encapsulated molecules, coumarin 102, from the nanoparticles under stimulation of UV light, acid and the combined stimuli could be realized.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acrylamides / chemistry
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Benzopyrans / chemistry*
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Drug Carriers / chemistry
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Dynamic Light Scattering
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Hydrogen-Ion Concentration
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Indoles / chemistry*
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Micelles
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Nanoparticles / chemistry*
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Nanoparticles / metabolism
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Nanoparticles / ultrastructure
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Nitro Compounds / chemistry*
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Polymers / chemistry*
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Temperature
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Ultraviolet Rays*
Substances
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Acrylamides
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Benzopyrans
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Drug Carriers
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Indoles
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Micelles
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Nitro Compounds
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Polymers
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spiropyran
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N-isopropylacrylamide