Added value of morphologic characteristics on diffusion-weighted images for characterizing lymph nodes in primary rectal cancer

Clin Imaging. 2015 Nov-Dec;39(6):1046-51. doi: 10.1016/j.clinimag.2015.07.022. Epub 2015 Jul 19.

Abstract

To evaluate the added value of the morphologic features of lymph nodes (LNs) on diffusion-weighted images (DWI), an interval reading was performed for the T2-weighted images (T2WI) and the combined image set (T2WI and DWI) using extracted imaging characteristics from 54 metastatic and 172 benign LNs in 44 patients with primary rectal cancer. The specificity and accuracy increased after adding DWI to T2WI for both readers (specificity: from 59% to 73% and from 41% to 68% for readers 1 and 2, respectively; accuracy: from 58% to 68% and from 44% to 64% for readers 1 and 2, respectively, P<.0001).

Keywords: Diffusion-weighted magnetic resonance imaging; Lymph node; Lymphatic metastasis; Neoplasm; Rectum.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Diffusion Magnetic Resonance Imaging / methods*
  • Female
  • Humans
  • Lymph Nodes / pathology*
  • Male
  • Middle Aged
  • Rectal Neoplasms / pathology*
  • Retrospective Studies
  • Sensitivity and Specificity