Minimum Information about a Biosynthetic Gene cluster

Affiliations

• ¹ Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen, Germany.
• ² Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester, UK.
• ³ Laboratory of Genetically Encoded Small Molecules, Howard Hughes Medical Institute, The Rockefeller University, New York, New York, USA.
• ⁴ Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark.
• ⁵ Netherlands Institute of Ecology (NIOO-KNAW), Department of Microbial Ecology, Wageningen, the Netherlands.
• ⁶ 1] Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, California, USA. [2] Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California, USA. [3] School of Chemistry and Biochemistry, University of Western Australia, Perth, Western Australia, Australia.
• ⁷ 1] Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA. [2] California Institute for Quantitative Biosciences, University of California San Francisco, San Francisco, California, USA.
• ⁸ Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California, USA.
• ⁹ Evolution of Metabolic Diversity Laboratory, Unidad de Genómica Avanzada (Langebio), Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-IPN), Irapuato, Guanajuato, México.
• ¹⁰ Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany.
• ¹¹ Institute for Molecular Biosciences, Goethe University, Frankfurt am Main, Germany.
• ¹² Department of Chemistry and Biochemistry, California State University, Chico, California, USA.
• ¹³ Microbiology and Biotechnology Division, Department of Food and Environmental Sciences, University of Helsinki, Helsinki, Finland.
• ¹⁴ Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA.
• ¹⁵ Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, UK.
• ¹⁶ Department of Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.
• ¹⁷ School of Biosciences, University of Birmingham, Birmingham, UK.
• ¹⁸ Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Zürich, Switzerland.
• ¹⁹ Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
• ²⁰ Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany.
• ²¹ Gordon and Betty Moore Foundation, Palo Alto, California, USA.
• ²² Sustainable Studies Program, Roosevelt University Chicago, Illinois, USA.
• ²³ Merck Stiftungsprofessur für Molekulare Biotechnologie, Goethe Universität Frankfurt, Fachbereich Biowissenschaften, Frankfurt, Germany.
• ²⁴ 1] Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark. [2] BioInformatics Research Center, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
• ²⁵ 1] Laboratory of Gene Technology, KU Leuven, Heverlee, Belgium. [2] Laboratory of Food Microbiology, KU Leuven, Heverlee, Belgium.
• ²⁶ Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA.
• ²⁷ Department of Biology, William Paterson University, Wayne, New Jersey, USA.
• ²⁸ Department of Biology, Memorial University of Newfoundland, St. John's, Newfoundland, Canada.
• ²⁹ Department of Metabolic Biology, John Innes Centre, Norwich Research Park, Norwich, UK.
• ³⁰ Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, USA.
• ³¹ Institut für Chemie, Technische Universität Berlin, Berlin, Germany.
• ³² BIOMERIT Research Centre, School of Microbiology, University College Cork-National University of Ireland, Cork, Ireland.
• ³³ Departamento de Bioquímica y Genómica Microbianas, IBCE, Montevideo, Uruguay.
• ³⁴ 1] Energy Biosciences Institute, University of California Berkeley, Berkeley, California, USA. [2] Department of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, California, USA.
• ³⁵ State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.
• ³⁶ 1] Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany. [2] Department of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
• ³⁷ Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
• ³⁸ 1] Department of Molecular Biosciences, The University of Texas, Austin, Texas, USA. [2] Institute for Cellular and Molecular Biology, The University of Texas, Austin, Texas, USA.
• ³⁹ Department of Biochemistry and Biomedical Sciences, The M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.
• ⁴⁰ 1] Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [3] Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [4] Department of Microbiology &Immunology, University of Michigan, Ann Arbor, Michigan, USA.
• ⁴¹ Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China.
• ⁴² Dynamique des Génomes et Adaptation Microbienne, Université de Lorraine and Institut National de la Recherche Agronomique (INRA), Unité Mixte de Recherche (UMR) 1128, Vandœuvre-lès-Nancy, France.
• ⁴³ 1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany.
• ⁴⁴ Infectious Disease Research, Merck Research Laboratories, Kenilworth, New Jersey, USA.
• ⁴⁵ Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, USA.
• ⁴⁶ 1] Merck Stiftungsprofessur für Molekulare Biotechnologie, Goethe Universität Frankfurt, Fachbereich Biowissenschaften, Frankfurt, Germany. [2] Buchmann Institute for Molecular Life Sciences (BMLS), Goethe Universität Frankfurt, Frankfurt, Germany.
• ⁴⁷ Fachbereich Phytomedizin, Albrecht Thaer Institut, Humboldt Universität Berlin, Berlin, Germany.
• ⁴⁸ UCD School of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland.
• ⁴⁹ UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas, USA.
• ⁵⁰ Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA.
• ⁵¹ 1] Institut für Organische Chemie, Leibniz Universität Hannover, Hannover, Germany. [2] School of Chemistry, University of Bristol, Bristol, UK.
• ⁵² Centre of Microbial and Plant Genetics, Faculty of Bioscience Engineering, University of Leuven, Heverlee, Belgium.
• ⁵³ Naicons Srl, Milano, Italy.
• ⁵⁴ Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA.
• ⁵⁵ 1] Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana-Champaign, Illinois, USA. [2] Howard Hughes Medical Institute, USA.
• ⁵⁶ 1] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. [2] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA. [3] Collaborative Mass Spectrometry Innovation Center, University of California San Diego, La Jolla, California, USA.
• ⁵⁷ Department of Biology, Maynooth University, Maynooth, County Kildare, Ireland.
• ⁵⁸ Department of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute and Zernike Institute for Advanced Materials, University of Groningen, Groningen, the Netherlands.
• ⁵⁹ Functional Microbiology, Institute of Microbiology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria.
• ⁶⁰ 1] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. [2] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA.
• ⁶¹ 1] Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany. [2] Friedrich Schiller University, Jena, Germany.
• ⁶² Department of Crop Protection, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
• ⁶³ Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada.
• ⁶⁴ Synthetic Biology Engineering Research Center (SynBERC), University of California Emeryville, Emeryville, California, USA.
• ⁶⁵ Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA.
• ⁶⁶ 1] Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA. [2] Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
• ⁶⁷ Institute of Molecular Biology, Slovak Academy of Sciences, Bratislava, Slovak Republic.
• ⁶⁸ Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, the Netherlands.
• ⁶⁹ Biotechnology Research Center, The University of Tokyo, Tokyo, Japan.
• ⁷⁰ 1] Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California, USA. [2] Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.
• ⁷¹ Division of Bioscience and Bioinformatics, Myongji University, Yongin-si, Gyeonggi-Do, South Korea.
• ⁷² Institute of Integrative Biology of the Cell (I2BC), Commissariat à l'Energie Atomique (CEA), Centre National de la Recherche Scientifique (CNRS), Université Paris Sud, Orsay, France.
• ⁷³ Laboratory of Gene Technology, KU Leuven, Heverlee, Belgium.
• ⁷⁴ Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
• ⁷⁵ 1] State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai, China. [2] School of Life Sciences &Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
• ⁷⁶ Department of Pharmaceutical Sciences, Oregon State University, Corvallis, Oregon, USA.
• ⁷⁷ Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen, Germany.
• ⁷⁸ 1] Departamento de Biología Funcional, Universidad de Oviedo, Oviedo, Spain. [2] Instituto Universitario de Oncología del Principado de Asturias (I.U.O.P.A), Universidad de Oviedo, Oviedo, Spain.
• ⁷⁹ Department of Biochemistry, University of Turku, Turku, Finland.
• ⁸⁰ School of Chemistry, University of Manchester, Manchester, UK.
• ⁸¹ Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana-Champaign, Illinois, USA.
• ⁸² Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal.
• ⁸³ School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.
• ⁸⁴ 1] Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark. [2] Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
• ⁸⁵ 1] BIOMERIT Research Centre, School of Microbiology, University College Cork-National University of Ireland, Cork, Ireland. [2] Curtin University, School of Biomedical Sciences, Perth, Western Australia, Australia.
• ⁸⁶ Division of Chemistry, Graduate School of Science, Hokkaido University, Sapporo, Japan.
• ⁸⁷ Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
• ⁸⁸ Department of Genetics and Biotechnology, Ivan Franko National University of Lviv, Lviv, Ukraine.
• ⁸⁹ Institute of Microbiology, Academy of Sciences of the Czech Republic (ASCR), Prague, Czech Republic.
• ⁹⁰ Laboratoire Interdisciplinaire des Energies de Demain (LIED), UMR 8236 CNRS, Université Paris Diderot, Paris, France.
• ⁹¹ Departamento de Biología Funcional, Universidad de Oviedo, Oviedo, Spain.
• ⁹² Novartis Institutes for BioMedical Research, Novartis Campus, Basel, Switzerland.
• ⁹³ Institute of Fundamental Sciences, Massey University, Palmerston North, New Zealand.
• ⁹⁴ Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.
• ⁹⁵ 1] Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, USA. [2] Molecular Therapeutics and Natural Products Library Initiative, The Scripps Research Institute, Jupiter, Florida, USA.
• ⁹⁶ 1] Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota-Twin Cities, Saint Paul, Minnesota, USA. [2] BioTechnology Institute, University of Minnesota-Twin Cities, Saint Paul, Minnesota, USA.
• ⁹⁷ 1] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany. [2] Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen, Germany.
• ⁹⁸ 1] Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, California, USA. [2] Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California, USA.
• ⁹⁹ Unité BIOlogie et GEstion des Risques en agriculture (BIOGER), Institut National de la Recherche Agronomique (INRA), Grignon, France.
• ¹⁰⁰ Department of Energy Great Lakes Bioenergy Research Center and Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan, USA.
• ¹⁰¹ Chemistry, Engineering &Medicine for Human Health (ChEM-H) Institute, Stanford University, Stanford, California, USA.
• ¹⁰² Molecular Biotechnology, Institute of Biology, Leiden University, Leiden, the Netherlands.
• ¹⁰³ Hofstra North Shore-Long Island Jewish School of Medicine, Hempstead, New York, USA.
• ¹⁰⁴ Department of Biotechnology, Norwegian University of Science and Technology, Trondheim, Norway.
• ¹⁰⁵ 1] Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen, Germany. [2] Jacobs University Bremen gGmbH, Bremen, Germany.