Transcatheter Versus Surgical Closure of Atrial Septal Defects in Children: A Value Comparison

JACC Cardiovasc Interv. 2016 Jan 11;9(1):79-86. doi: 10.1016/j.jcin.2015.09.028.

Abstract

Objectives: The purpose of this study was to determine whether a transcatheter procedure or surgical closure offers a better value proposition for atrial septal defect (ASD) closure.

Background: Secundum ASDs are common congenital heart defects with both transcatheter and surgical treatment options. Although both options have been shown to have excellent results in children, the relative value of the 2 procedures is unclear.

Methods: Using data from the Pediatric Hospital Information System for 2004 to 2012, we compared the value of transcatheter versus surgical ASD closure for children ages 1 to 17 years, with value being defined as outcomes relative to costs. Total charges for procedure-related encounters were converted to costs using hospital-specific cost-to-charge ratios, and all costs were adjusted for inflation to reflect 2012 dollars.

Results: There were 4,606 transcatheter procedures and 3,159 surgeries at 35 children's hospitals. Those undergoing transcatheter closure were more likely to be older (5.6 years vs. 4.5 years, p < 0.0001). There was no mortality in either group. Children with a surgical procedure had a longer length of stay (4.0 days vs. 1.5 days, p < 0.0001), were more likely to have an infection (odds ratio: 3.73, p < 0.0001) or procedural complication (odds ratio: 6.66, p < 0.0001). Costs for transcatheter procedure encounters were lower than costs for surgical encounters (mean of $19,128 vs. $25,359, p < 0.0001).

Conclusions: Both transcatheter and surgical ASD closure had excellent short-term outcomes, but transcatheter procedures had lower lengths of stay, rates of infection, and complications, resulting in lower overall costs. For children who are eligible, transcatheter ASD closure provides better short-term value than surgery.

Keywords: atrial septal defect; outcome; surgery; transcatheter; value.

Publication types

  • Comparative Study
  • Multicenter Study

MeSH terms

  • Adolescent
  • Age Factors
  • Cardiac Catheterization* / adverse effects
  • Cardiac Catheterization* / economics
  • Cardiac Catheterization* / instrumentation
  • Cardiac Surgical Procedures* / adverse effects
  • Cardiac Surgical Procedures* / economics
  • Cardiac Surgical Procedures* / instrumentation
  • Child
  • Child, Preschool
  • Cost-Benefit Analysis
  • Female
  • Heart Septal Defects, Atrial / diagnosis
  • Heart Septal Defects, Atrial / economics
  • Heart Septal Defects, Atrial / surgery
  • Heart Septal Defects, Atrial / therapy*
  • Hospital Charges
  • Hospital Costs
  • Humans
  • Infant
  • Length of Stay
  • Linear Models
  • Male
  • Odds Ratio
  • Postoperative Complications / etiology
  • Retrospective Studies
  • Risk Factors
  • Septal Occluder Device
  • Time Factors
  • Treatment Outcome