Effect of Fiberoptic Collimation Technique on 808 nm Wavelength Laser Stimulation of Cochlear Neurons

Photomed Laser Surg. 2016 Jun;34(6):252-7. doi: 10.1089/pho.2015.4065. Epub 2016 Mar 15.

Abstract

Objective: The purpose of this study was to evaluate the effects of fiberoptic collimation technique on auditory neural stimulation in the cochlea with 808 nm wavelength lasers.

Background data: Recently, the pulsed near-infrared lasers in the 800-1000 nm wavelength range have been investigated as an emerging technique to trigger auditory neural response in the cochlea. A laser beam divergence in the optical stimulation pathway exists, which may affect stimulation efficiency and spatial selectivity.

Methods: The fiberoptic collimation technique was proposed for cochlear neuron stimulation, and the C-lens element was designed as the collimation structure. The spiral ganglion cells in deafened guinea pigs' cochlea were irradiated with collimated and uncollimated near-infrared lasers. Optically evoked auditory brainstem response (OABR) under the two laser output modes were recorded.

Results: Laser with the collimation technique evoked an average 58% higher OABR amplitude than the uncollimated laser output. In addition, the collimated laser setup consumed on average 35.2% of laser energy compared with the uncollimated laser when evoking the same OABR amplitude.

Conclusions: The fiberoptic collimation technique improved stimulation efficiency and reduced stimulating energy consumption in near-infrared neural stimulation in cochlea. The positive effects of laser collimation technique could benefit further research in optically based cochlear implants.

MeSH terms

  • Acoustic Stimulation / methods*
  • Animals
  • Cochlea / radiation effects*
  • Cochlear Nerve / radiation effects*
  • Evoked Potentials, Auditory, Brain Stem
  • Fiber Optic Technology*
  • Guinea Pigs
  • Infrared Rays*
  • Lasers*
  • Neurons / radiation effects*