Nonprosthesis Orthopedic Applications of (18)F Fluoro-2-Deoxy-d-Glucose PET in the Detection of Osteomyelitis

Johannes Meller; Carsten Oliver Sahlmann; Torsten Liersch; Peter Hao Tang; Abass Alavi

doi:10.1016/j.cpet.2006.01.004

Nonprosthesis Orthopedic Applications of (18)F Fluoro-2-Deoxy-d-Glucose PET in the Detection of Osteomyelitis

PET Clin. 2006 Apr;1(2):107-21. doi: 10.1016/j.cpet.2006.01.004. Epub 2006 May 6.

Authors

Johannes Meller¹, Carsten Oliver Sahlmann¹, Torsten Liersch², Peter Hao Tang³, Abass Alavi³

Affiliations

¹ Department of Nuclear Medicine, University of Göttingen, Robert Koch-Straße 40, D- 37075, Göttingen, Germany.
² Department of General Surgery, University of Göttingen, Göttingen, Germany.
³ Division of Nuclear Medicine, Department of Radiology, Hospital of the University of Pennsylvania, 110 Donner Building, 3400 Spruce Street, Philadelphia, PA 19104, USA.

PMID: 27157077
DOI: 10.1016/j.cpet.2006.01.004

Abstract

This article describes the impact of [(18)F]2-fluoro-2-deoxy-d-glucose (FDG) PET in the diagnosis of non-prosthesis-related orthopedic infections and inflammation. FDG-PET has an excellent sensitivity in the detection of osteomyelitis (OM). Early data indicate that FDG-PET may be more specific than MRI in diagnosing OM. The role of the combination of FDG and PET-CT in the diagnosis of OM is likely to be determined as this combination is used on a routine basis. Early data from studies in rheumatoid arthritis indicate that FDG-PET is highly accurate in early diagnosis and that it provides results comparable to the most advanced conventional techniques.