1 Medical Affairs, BC Children's Hospital and Sunny Hill Health Centre, BCCH and UBC Global Child Health, Vancouver, BC, Canada; Department of Pediatrics, Global Sepsis Alliance; and Department of Paediatrics and Emergency Medicine, University of British Columbia, Child and Family Research Institute, Vancouver, BC, Canada; Critical Care, United Kingdom, Department of Critical Care and Anesthesia, Global Sepsis Alliance; and UK Sepsis Trust; Division of Infectious Diseases and Center for Experimental and Molecular Medicine, Department of Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Intensive Care, Royal North Shore Hospital, Sydney, NSW, Australia; and Department of Critical Care and Anesthesia, International Sepsis Forum and Global Sepsis Alliance; Anaesthesiology and Intensive Care, Jena University Hospital, Jena, Germany; and Department of Critical Care and Anesthesia, Global Sepsis Alliance.