Evaluation and Treatment of Osteoporosis

Med Clin North Am. 2016 Jul;100(4):807-26. doi: 10.1016/j.mcna.2016.03.016. Epub 2016 Apr 20.

Abstract

As the population ages, the rates of osteoporotic fractures will increase, with postmenopausal women incurring most of these fractures. Diagnosis and treatment of osteoporosis are extremely important. Dual-energy x-ray absorptiometry scan screening is recommended in all women more than 65 years of age or in women aged 50 to 64 years with certain risk factors. Treatment should be considered if osteoporosis is present, there is a history of fragility fracture, or in the setting of osteopenia plus high risk for fracture.

Keywords: Diagnosis; Men; Osteoporosis; Postmenopausal women; Screening; Treatment.

Publication types

  • Review

MeSH terms

  • Absorptiometry, Photon
  • Adrenal Cortex Hormones / adverse effects
  • Age Factors
  • Aged
  • Alcohol Drinking / epidemiology
  • Bone Density
  • Bone Density Conservation Agents / administration & dosage
  • Bone Density Conservation Agents / adverse effects
  • Bone Density Conservation Agents / therapeutic use*
  • Calcium / therapeutic use
  • Denosumab / therapeutic use
  • Dietary Supplements
  • Diphosphonates / therapeutic use
  • Estrogen Replacement Therapy / methods*
  • Female
  • Humans
  • Male
  • Mass Screening / methods
  • Middle Aged
  • Osteoporosis / diagnosis
  • Osteoporosis / drug therapy*
  • Osteoporosis / epidemiology*
  • Osteoporotic Fractures / epidemiology
  • Osteoporotic Fractures / prevention & control
  • Risk Factors
  • Selective Estrogen Receptor Modulators / therapeutic use
  • Smoking / epidemiology
  • Vitamin D / therapeutic use

Substances

  • Adrenal Cortex Hormones
  • Bone Density Conservation Agents
  • Diphosphonates
  • Selective Estrogen Receptor Modulators
  • Vitamin D
  • Denosumab
  • Calcium