OsASR5 enhances drought tolerance through a stomatal closure pathway associated with ABA and H2 O2 signalling in rice

Plant Biotechnol J. 2017 Feb;15(2):183-196. doi: 10.1111/pbi.12601. Epub 2016 Nov 11.

Abstract

Drought is one of the major abiotic stresses that directly implicate plant growth and crop productivity. Although many genes in response to drought stress have been identified, genetic improvement to drought resistance especially in food crops is showing relatively slow progress worldwide. Here, we reported the isolation of abscisic acid, stress and ripening (ASR) genes from upland rice variety, IRAT109 (Oryza sativa L. ssp. japonica), and demonstrated that overexpression of OsASR5 enhanced osmotic tolerance in Escherichia coli and drought tolerance in Arabidopsis and rice by regulating leaf water status under drought stress conditions. Moreover, overexpression of OsASR5 in rice increased endogenous ABA level and showed hypersensitive to exogenous ABA treatment at both germination and postgermination stages. The production of H2 O2 , a second messenger for the induction of stomatal closure in response to ABA, was activated in overexpression plants under drought stress conditions, consequently, increased stomatal closure and decreased stomatal conductance. In contrast, the loss-of-function mutant, osasr5, showed sensitivity to drought stress with lower relative water content under drought stress conditions. Further studies demonstrated that OsASR5 functioned as chaperone-like protein and interacted with stress-related HSP40 and 2OG-Fe (II) oxygenase domain containing proteins in yeast and plants. Taken together, we suggest that OsASR5 plays multiple roles in response to drought stress by regulating ABA biosynthesis, promoting stomatal closure, as well as acting as chaperone-like protein that possibly prevents drought stress-related proteins from inactivation.

Keywords: ABA; Oryza sativa; OsASR5; Drought; stomata; water content.

MeSH terms

  • Abscisic Acid / metabolism
  • Abscisic Acid / pharmacology
  • Arabidopsis / enzymology
  • Arabidopsis / genetics
  • Arabidopsis / metabolism*
  • Droughts*
  • Escherichia coli / genetics
  • Genes, Plant
  • Germination
  • HSP40 Heat-Shock Proteins / genetics
  • HSP40 Heat-Shock Proteins / metabolism
  • Hydrogen Peroxide / metabolism*
  • Mutation
  • Oryza / enzymology
  • Oryza / genetics
  • Oryza / metabolism*
  • Plant Proteins / genetics*
  • Plant Proteins / metabolism
  • Plant Stomata / metabolism*
  • Plants, Genetically Modified
  • Stress, Physiological / genetics
  • Stress, Physiological / physiology*
  • Transcription Factors / genetics
  • Transcription Factors / metabolism
  • Water / metabolism

Substances

  • HSP40 Heat-Shock Proteins
  • Plant Proteins
  • Transcription Factors
  • Water
  • Abscisic Acid
  • Hydrogen Peroxide