A case of non-specific interstitial pneumonia with recurrent gastric carcinoma and anti-Jo-1 antibody positive myositis

Respir Investig. 2016 Jul;54(4):289-93. doi: 10.1016/j.resinv.2016.02.005. Epub 2016 Mar 17.

Abstract

We report the first case of non-specific interstitial pneumonia (NSIP) in a patient with cancer-associated myositis (CAM) that emerged along with the recurrence of the cancer. A 60-year-old woman, with a history of partial gastrectomy for gastric cancer 11 years ago, presented with exertional dyspnea with anti-Jo-1 antibody-positive myositis. Surgical lung biopsy showed NSIP with metastatic gastric cancer. Accordingly, her condition was diagnosed as CAM with cancer recurrence. In patients with a history of cancer, development of myositis may indicate cancer recurrence; therefore, careful observation would be necessary.

Keywords: Anti-synthetase syndrome; Jo-1; Myositis; Neoplasm; Non-specific interstitial pneumonia.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Antinuclear / immunology*
  • Female
  • Humans
  • Lung Diseases, Interstitial / complications
  • Middle Aged
  • Myositis / immunology*
  • Stomach Neoplasms / complications*

Substances

  • Antibodies, Antinuclear
  • Jo-1 antibody