Altered metabolic profile in patients with IgE to galactose-alpha-1,3-galactose following in vivo food challenge

J Allergy Clin Immunol. 2016 Nov;138(5):1465-1467.e8. doi: 10.1016/j.jaci.2016.05.021. Epub 2016 Jun 15.

Abstract

Determination of metabolic changes that occur following the development of and after red meat challenge in alpha-gal allergic individuals will aid in biomarkers for patient identification and targeted therapeutic development.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Allergens / immunology
  • Anaphylaxis / immunology
  • Anaphylaxis / metabolism
  • Biomarkers / metabolism
  • Case-Control Studies
  • Female
  • Food Hypersensitivity / immunology*
  • Food Hypersensitivity / metabolism*
  • Galactose / immunology*
  • Humans
  • Immunoglobulin E / immunology*
  • Male
  • Metabolome / physiology*
  • Oligosaccharides / immunology
  • Urticaria / immunology
  • Urticaria / metabolism

Substances

  • Allergens
  • Biomarkers
  • Oligosaccharides
  • Immunoglobulin E
  • Galactose