Abstract
There has been a rapid expansion in use of transgenic technologies in zebrafish. We report a novel example of transinteractions of genetic elements, or transvection. This interaction led to a novel expression pattern and illustrates a precautionary example regarding use of transgenes in zebrafish.
Keywords:
Gal4; UAS; transgenic; transvection; zebrafish.
MeSH terms
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Animals
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Animals, Genetically Modified / genetics*
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Animals, Genetically Modified / growth & development
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Animals, Genetically Modified / metabolism
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Epistasis, Genetic*
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Gene Expression Regulation
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Green Fluorescent Proteins / genetics
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Green Fluorescent Proteins / metabolism*
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Humans
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Potassium Channels, Inwardly Rectifying / genetics
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Potassium Channels, Inwardly Rectifying / metabolism
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Promoter Regions, Genetic
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Regulatory Sequences, Nucleic Acid*
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Transgenes*
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Zebrafish / genetics*
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Zebrafish / growth & development
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Zebrafish / metabolism
Substances
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KCNJ2 protein, human
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Potassium Channels, Inwardly Rectifying
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Green Fluorescent Proteins