Two cases of pseudo-achalasia with lung cancer: Case report and short literature review

Respir Investig. 2016 Nov;54(6):494-499. doi: 10.1016/j.resinv.2016.04.006. Epub 2016 Jul 15.

Abstract

Pseudo-achalasia with lung cancer is a rare complication. We present 2 cases of pseudo-achalasia with lung cancer and summarize previous reports. The previous reports suggested that lung cancer can be complicated with pseudo-achalasia caused by paraneoplastic neurological syndromes rather than direct invasion of the tumor cells to the lower esophageal sphincter, irrespective of the histology of the lung cancer; this can strongly influence the performance status. Treatment for pseudo-achalasia improves not only the symptoms, but also the performance status. Therefore, pseudo-achalasia should be considered when lung cancer patients present with dysphagia without other known causes.

Keywords: Lung cancer; Paraneoplastic neurological syndromes; Pseudo-achalasia; Secondary achalasia.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma / complications*
  • Aged
  • Carcinoma, Squamous Cell / complications*
  • Carcinoma, Squamous Cell / diagnosis
  • Deglutition Disorders / etiology
  • Esophageal Achalasia / diagnosis*
  • Esophageal Achalasia / diagnostic imaging
  • Esophageal Achalasia / etiology*
  • Esophageal Achalasia / surgery
  • Female
  • Fluoroscopy
  • Gastrostomy
  • Humans
  • Lung Neoplasms / complications*
  • Lung Neoplasms / diagnosis
  • Male
  • Paraneoplastic Syndromes, Nervous System / complications
  • Radiography, Thoracic
  • Tomography, X-Ray Computed