Abstract
Urinary tract infections (UTI) caused by organisms resistant to trimethoprim (TMP), as well as their faecal carriage were studied in two geriatric wards. TMP-resistant UTI was common (26 and 50% of admission and ward-acquired infections, respectively) and was associated with male sex, recurrent and transferred admissions and length of stay. There was a strong relationship between faecal carriage and isolation of TMP-resistant organisms from urine. Antimicrobial exposure was the major determinant of TMP-resistant faecal carriage.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Aged, 80 and over
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Bacterial Infections / drug therapy*
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Bacterial Infections / epidemiology
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Bacterial Infections / microbiology
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Cross Infection / drug therapy*
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Cross Infection / epidemiology
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Cross Infection / microbiology
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Drug Resistance, Microbial
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England
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Feces / microbiology
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Female
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Gram-Negative Bacteria / drug effects*
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Humans
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Male
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Risk Factors
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Trimethoprim / therapeutic use*
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Urinary Tract Infections / drug therapy*
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Urinary Tract Infections / epidemiology
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Urinary Tract Infections / microbiology