SNX2-ABL1-positive acute lymphoblastic leukemia possibly has a poor prognosis

Leuk Lymphoma. 2017 Sep;58(9):1-3. doi: 10.1080/10428194.2017.1287357. Epub 2017 Feb 9.

Authors

Qitian Mu¹, Lieping Guo², Yongxian Hu³, Lixia Sheng⁴, Yi Zhang¹, Ningning Wu¹, Ying Chen¹, Cong Shi¹, Songqiu Shi¹, Ying Wu¹, Guifang Ouyang^{1

4}

Affiliations

¹ a Laboratory of Stem Cell Transplantation , Ningbo First Hospital , Zhejiang , P.R. China.
² b Department of Oncology , Eastern Hepatobiliary Hospital, Third Affiliated Hospital of Second Military Medical University , Shanghai , P.R. China.
³ c Bone Marrow Transplantation Center , The First Affiliated Hospital, School of Medicine, Zhejiang University , Hangzhou , P.R. China.
⁴ d Hematology Department , Ningbo First Hospital , Zhejiang , P.R. China.

PMID: 28278724
DOI: 10.1080/10428194.2017.1287357

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Antineoplastic Combined Chemotherapy Protocols / adverse effects
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Biomarkers, Tumor*
DNA Mutational Analysis
Fatal Outcome
Gene Dosage
Genotype
Hematopoietic Stem Cell Transplantation
Humans
Male
Oncogene Proteins, Fusion / genetics*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis
Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / mortality*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy
Prognosis
Proto-Oncogene Proteins c-abl / genetics*
Sorting Nexins / genetics*
Translocation, Genetic

Substances

Biomarkers, Tumor
Oncogene Proteins, Fusion
SNX2 protein, human
Sorting Nexins
Proto-Oncogene Proteins c-abl