The 'across the pons' sign: A possible novel radiographic finding in natalizumab-associated progressive multifocal leukoencephalopathy

J Neurol Sci. 2017 Apr 15:375:304-306. doi: 10.1016/j.jns.2017.02.021. Epub 2017 Feb 10.

Authors

A Budhram¹, J B Pelikan², M Kremenchutzky², M Sharma³

Affiliations

¹ Department of Clinical Neurological Sciences, London Health Sciences Centre, London, Ontario, Canada. Electronic address: [email protected].
² Department of Clinical Neurological Sciences, London Health Sciences Centre, London, Ontario, Canada.
³ Department of Medical Imaging, London Health Sciences Centre, London, Ontario, Canada.

PMID: 28320156
DOI: 10.1016/j.jns.2017.02.021

No abstract available

Keywords: Across the pons sign; Hot-cross bun sign; MRI; Multiple sclerosis; Natalizumab; Progressive multifocal leukoencephalopathy.

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Brain / diagnostic imaging*
Brain / drug effects
Contrast Media
Diagnosis, Differential
Female
Gadolinium
Humans
Immunologic Factors / adverse effects*
Immunologic Factors / therapeutic use
Leukoencephalopathy, Progressive Multifocal / diagnostic imaging*
Leukoencephalopathy, Progressive Multifocal / etiology*
Magnetic Resonance Imaging*
Multiple Sclerosis, Relapsing-Remitting / diagnostic imaging
Multiple Sclerosis, Relapsing-Remitting / drug therapy
Natalizumab / adverse effects*
Natalizumab / therapeutic use

Substances

Contrast Media
Immunologic Factors
Natalizumab
Gadolinium

Grants and funding

LHR H0153/CIHR/Canada