Podophyllotoxins for brain metastases of small cell lung cancer

J Neurooncol. 1988 Nov;6(3):231-2. doi: 10.1007/BF00163706.

Abstract

A patient with brain metastases of small cell lung cancer (SCLC) responded initially to cranial irradiation. Recurrences were subsequently successfully treated with high-dose intravenous etoposide (VP 16-213) and teniposide (VM 26). Epipodophyllotoxins are potentially useful for CNS metastases of SCLC.

Publication types

  • Case Reports

MeSH terms

  • Brain Neoplasms / drug therapy*
  • Brain Neoplasms / radiotherapy
  • Brain Neoplasms / secondary
  • Carcinoma, Small Cell / drug therapy*
  • Carcinoma, Small Cell / radiotherapy
  • Carcinoma, Small Cell / secondary
  • Etoposide / therapeutic use*
  • Humans
  • Lung Neoplasms / drug therapy*
  • Male
  • Middle Aged
  • Podophyllotoxin / analogs & derivatives*
  • Teniposide / therapeutic use*

Substances

  • Etoposide
  • Teniposide
  • Podophyllotoxin