PET/MR Imaging in Gynecologic Oncology

Michael A Ohliger; Thomas A Hope; Jocelyn S Chapman; Lee-May Chen; Spencer C Behr; Liina Poder

doi:10.1016/j.mric.2017.03.012

PET/MR Imaging in Gynecologic Oncology

Magn Reson Imaging Clin N Am. 2017 Aug;25(3):667-684. doi: 10.1016/j.mric.2017.03.012. Epub 2017 May 27.

Authors

Michael A Ohliger¹, Thomas A Hope², Jocelyn S Chapman³, Lee-May Chen³, Spencer C Behr⁴, Liina Poder⁴

Affiliations

¹ Department of Radiology and Biomedical Imaging, University of California, San Francisco, 505 Parnassus Avenue, M-391, San Francisco, CA 94143-0628, USA; Department of Radiology, Zuckerberg San Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110, USA. Electronic address: [email protected].
² Department of Radiology and Biomedical Imaging, University of California, San Francisco, 505 Parnassus Avenue, M-391, San Francisco, CA 94143-0628, USA; Department of Radiology, San Francisco Veterans Affairs Hospital, Box VAMC, 4150 Clement Street, 2D007, San Francisco, CA 94121, USA.
³ Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, 1825 Fourth Street, Third Floor, San Francisco, CA 94158, USA.
⁴ Department of Radiology and Biomedical Imaging, University of California, San Francisco, 505 Parnassus Avenue, M-391, San Francisco, CA 94143-0628, USA.

PMID: 28668166
DOI: 10.1016/j.mric.2017.03.012

Abstract

MR imaging and PET using 2-Deoxy-2-[¹⁸F]fluoroglucose (FDG) are both useful in the evaluation of gynecologic malignancies. MR imaging is superior for local staging of disease whereas fludeoxyglucose FDG PET is superior for detecting distant metastases. Integrated PET/MR imaging scanners have great promise for gynecologic malignancies by combining the advantages of each modality into a single scan. This article reviews the technology behind PET/MR imaging acquisitions and technical challenges relevant to imaging the pelvis. A dedicated PET/MR imaging protocol; the roles of PET and MR imaging in cervical, endometrial, and ovarian cancers; and future directions for PET/MR imaging are discussed.

Keywords: Cervical cancer; Endometrial cancer; Gynecology; MR imaging; Ovarian cancer; PET; PET/MR imaging.

Publication types

Review

MeSH terms

Female
Genital Neoplasms, Female / diagnostic imaging*
Genitalia, Female / diagnostic imaging
Humans
Magnetic Resonance Imaging / methods*
Multimodal Imaging / methods*
Positron-Emission Tomography / methods*