Anesthetic management for intestinal transplantation: A decade of experience

Clin Transplant. 2017 Oct;31(10). doi: 10.1111/ctr.13085. Epub 2017 Sep 21.

Abstract

Background: Intestinal transplantation (ITx) is the definitive therapy for patients suffering from intestinal failure. Previously published reports suggest that these cases should be managed perioperatively with the same intensive monitors and techniques as in liver transplantation.

Methods: We retrospectively reviewed the anesthetic management of 67 isolated intestinal, intestinal-pancreas, and intestinal-kidney transplants over the previous decade (2005-2015) in our tertiary care institution.

Results: Patients were typically managed with a single arterial line, a single central venous catheter, and rarely intensive modalities such as a pulmonary artery catheter, a transesophageal echocardiography, a second arterial catheter or central venous catheter, a rapid infusion system, a cell salvage device, or viscoelastic testing. Significant hemodynamic derangements were rare, and the rate of postreperfusion syndrome was 8.96%. Our fluid administration type and volume and transfusion type and volume were similar to previous reports in which more intensive anesthetic management was employed.

Conclusion: We demonstrate that ITx can safely occur without utilizing the intensive resources requisite for a liver transplant.

Keywords: clinical decision-making; coagulation and hemostasis; quality of care/care delivery; transfusion; transplantation.

MeSH terms

  • Adult
  • Anesthetics / administration & dosage*
  • Disease Management
  • Female
  • Follow-Up Studies
  • Humans
  • Intestines / transplantation*
  • Kidney Transplantation / mortality*
  • Liver Transplantation / mortality*
  • Male
  • Middle Aged
  • Postoperative Complications / mortality*
  • Prognosis
  • Retrospective Studies
  • Risk Factors
  • Survival Rate

Substances

  • Anesthetics