Distribution of serum levels of persistent organic pollutants, heterocyclic aromatic amine theoretical intake and nutritional cofactors in a semi-rural island population

Environ Sci Pollut Res Int. 2017 Oct;24(28):22393-22401. doi: 10.1007/s11356-017-9851-2. Epub 2017 Aug 12.

Abstract

Persistent organic pollutant (POP) exposure is strongly associated with negative health effects in humans. Heterocyclic aromatic amines (HAAs) are formed during high temperature cooking of foods (i.e. meat and fish). Human exposure to HAA is through food consumption and from similar food groups to POPs. A study of serum samples for POPs in a non-occupational exposed population (n = 149, age range 18-80 years, recruited in 2012) and comparison with estimated HAA daily intake calculations based on food diaries were undertaken. Three different age groups (group 1, 18-29 years; group 2, 30-44 years; and group 3, 45-80 years) were used to explore possible relationships between POP levels present in blood, HAA intake and nutritional cofactors. Significant differences (p < 0.05) between groups (1 and 3) for POP levels were found for p,p'-DDE, polychlorinated biphenyl (PCB) 153, PCB 138 and the sum of PCBs. A similar trend was found between groups 2 and 3 for PCB 153 and sum of PCBs. Significant differences were found between groups 1 and 3 and groups 2 and 3 for HAA intake., i.e. HAA intake was lowest in those of middle age, which may well reflect a different pathway of human exposure between HAA and POPs through the diet preferences.

Keywords: Estimated daily intake; Food diaries; HAA; Human exposure; Nutritional cofactors; POPs.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Dichlorodiphenyl Dichloroethylene / blood*
  • Environmental Exposure / analysis*
  • Environmental Pollutants / blood*
  • Feeding Behavior
  • Female
  • Humans
  • Middle Aged
  • Northern Ireland
  • Nutrition Assessment*
  • Polychlorinated Biphenyls / blood*
  • Rural Population*
  • Young Adult

Substances

  • Environmental Pollutants
  • Dichlorodiphenyl Dichloroethylene
  • Polychlorinated Biphenyls