Host and pathogen interface: microRNAs are modulators of disease outcome

Michael R Eledge; Laxmi Yeruva

doi:10.1016/j.micinf.2017.08.002

Host and pathogen interface: microRNAs are modulators of disease outcome

Microbes Infect. 2018 Aug-Sep;20(7-8):410-415. doi: 10.1016/j.micinf.2017.08.002. Epub 2017 Sep 7.

Authors

Michael R Eledge¹, Laxmi Yeruva²

Affiliations

¹ Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA; Arkansas Children's Research Institute, Little Rock, AR, USA; Arkansas Children's Nutrition Center, Little Rock, AR, USA.
² Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA; Arkansas Children's Research Institute, Little Rock, AR, USA; Arkansas Children's Nutrition Center, Little Rock, AR, USA. Electronic address: [email protected].

PMID: 28889971
DOI: 10.1016/j.micinf.2017.08.002

Abstract

Chlamydiae are a group of intracellular bacterium that infect a range of hosts and are responsible for the most common sexual transmitted infections, which could be the result of a plethora of factors leading to varied pathological outcomes. This review aims to show that Chlamydia possibly manipulates host defenses through microRNAs interaction.

Keywords: Chlamydia; Pathogenesis; micro-RNA (miRNA).

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Chlamydia / pathogenicity
Chlamydia / physiology*
Chlamydia Infections / immunology
Chlamydia Infections / microbiology*
Gene Expression
Host-Pathogen Interactions*
Humans
MicroRNAs / biosynthesis
MicroRNAs / genetics
MicroRNAs / metabolism*
Models, Biological
Signal Transduction / immunology

Substances

MicroRNAs