Microwave-assisted synthesis of novel hetero[5]helicene-like molecules and coumarin derivatives

Org Biomol Chem. 2017 Sep 26;15(37):7909-7916. doi: 10.1039/c7ob01742a.

Abstract

A concise and efficient approach to design and synthesize hetero[5]helicene-like molecules and coumarin derivatives is reported. Intriguingly, using the same catalyst (silica sulfuric acid), and a different solvent and reaction temperature, the reaction selectively afforded hetero[5]helicene-like molecules 3 or coumarin derivatives 4. Product 4 has a highly planar geometry, and product 3 can be regarded as hetero[5]helicene-like because of its helical conformation.

MeSH terms

  • Coumarins / chemical synthesis*
  • Coumarins / chemistry
  • Microwaves*
  • Molecular Structure
  • Polycyclic Compounds / chemical synthesis*
  • Polycyclic Compounds / chemistry

Substances

  • Coumarins
  • Polycyclic Compounds
  • helicenes