The role of acute circulatory support in ST-segment elevation myocardial infarction complicated by cardiogenic shock

Indian Heart J. 2017 Sep-Oct;69(5):668-674. doi: 10.1016/j.ihj.2017.05.011. Epub 2017 May 22.

Abstract

In the setting of ST-segment elevation myocardial infarction (STEMI) complicated by cardiogenic shock, three primary treatment objectives include providing circulatory support, ventricular unloading, and restoring myocardial perfusion. In addition to primary percutaneous coronary intervention, each of these three objectives can be achieved with appropriate use of an acute mechanical circulatory support (AMCS) pump. Over the past decade, utilization of percutaneously-delivered AMCS devices including the Impella axial-flow catheter, TandemHeart left atrial-to-femoral artery bypass system, and veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has grown exponentially. In this review, we will discuss the hemodynamic impact of each AMCS device and clinical data surrounding their use in the setting of STEMI complicated by cardiogenic shock.

Keywords: Acute myocardial infarction; Hemodynamics; Mechanical circulatory support.

Publication types

  • Review

MeSH terms

  • Extracorporeal Membrane Oxygenation / methods*
  • Heart-Assist Devices*
  • Hemodynamics / physiology*
  • Humans
  • ST Elevation Myocardial Infarction / complications*
  • Shock, Cardiogenic* / etiology
  • Shock, Cardiogenic* / physiopathology
  • Shock, Cardiogenic* / therapy
  • Treatment Outcome