Closed Genome Sequence of Chryseobacterium piperi Strain CTMT/ATCC BAA-1782, a Gram-Negative Bacterium with Clostridial Neurotoxin-Like Coding Sequences

Travis G Wentz; Tim Muruvanda; Sara Lomonaco; Nagarajan Thirunavukkarasu; Maria Hoffmann; Marc W Allard; David R Hodge; Segaran P Pillai; Thomas S Hammack; Eric W Brown; Shashi K Sharma

doi:10.1128/genomeA.01296-17

Closed Genome Sequence of Chryseobacterium piperi Strain CTM^T/ATCC BAA-1782, a Gram-Negative Bacterium with Clostridial Neurotoxin-Like Coding Sequences

Genome Announc. 2017 Nov 30;5(48):e01296-17. doi: 10.1128/genomeA.01296-17.

Affiliations

¹ Division of Microbiology, Office of Regulatory Science, Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, Maryland, USA.
² Chemical and Biological Defense Division, Department of Homeland Security, Washington, DC, USA.
³ Office of Laboratory Science and Safety, Food and Drug Administration, Silver Spring, Maryland, USA.
⁴ Division of Microbiology, Office of Regulatory Science, Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, Maryland, USA [email protected].

Abstract

Clostridial neurotoxins, including botulinum and tetanus neurotoxins, are among the deadliest known bacterial toxins. Until recently, the horizontal mobility of this toxin gene family appeared to be limited to the genus Clostridium We report here the closed genome sequence of Chryseobacterium piperi, a Gram-negative bacterium containing coding sequences with homology to clostridial neurotoxin family proteins.