What About the Girls? Sex-Based Differences in Autistic Traits and Adaptive Skills

J Autism Dev Disord. 2018 May;48(5):1698-1711. doi: 10.1007/s10803-017-3413-9.

Abstract

There is growing evidence of a camouflaging effect among females with autism spectrum disorder (ASD), particularly among those without intellectual disability, which may affect performance on gold-standard diagnostic measures. This study utilized an age- and IQ-matched sample of school-aged youth (n = 228) diagnosed with ASD to assess sex differences on the ADOS and ADI-R, parent-reported autistic traits, and adaptive skills. Although females and males were rated similarly on gold-standard diagnostic measures overall, females with higher IQs were less likely to meet criteria on the ADI-R. Females were also found to be significantly more impaired on parent reported autistic traits and adaptive skills. Overall, the findings suggest that some autistic females may be missed by current diagnostic procedures.

Keywords: Adaptive skills; Autism spectrum disorder; Diagnosis; Sex differences.

MeSH terms

  • Adaptation, Psychological / physiology*
  • Adolescent
  • Autism Spectrum Disorder / diagnosis*
  • Autism Spectrum Disorder / psychology*
  • Case-Control Studies
  • Child
  • Female
  • Humans
  • Intellectual Disability / diagnosis
  • Intellectual Disability / psychology
  • Male
  • Parents / psychology
  • Sex Characteristics*
  • Surveys and Questionnaires / standards*