Case: A forty-three-year-old male patient complained of difficulty walking due to severe hip and knee pain and stiffness, which had persisted for twenty years. He was found to have multifocal melorheostosis involving the axial skeleton and the entire left lower limb, along with complex vascular and lymphatic malformations corresponding to the sclerotomes related to the skeletal anomalies. Total hip and knee arthroplasties were performed. He was eventually free of pain during walking, and joint motion of the hip and knee was substantially improved after surgery.
Conclusion: Hip and knee pain and contracture resulting from multifocal melorheostosis were successfully treated with total hip and knee arthroplasty.