Unintended Consequences of Pretransplant Vancomycin-Resistant Enterococcus Screening on Antimicrobial Stewardship Among Allogeneic Hematopoietic Cell Transplant Recipients

Infect Control Hosp Epidemiol. 2018 Jun;39(6):730-733. doi: 10.1017/ice.2018.43. Epub 2018 Mar 28.

Abstract

We examined vancomycin-resistant enterococci (VRE)-directed antimicrobial use and VRE bacteremia in a cohort of allogeneic hematopoietic cell transplantation patients from a center where VRE screening is standard prior to transplant. In this cohort, VRE bacteremia (VREB) was infrequent. In patients without VREB, colonized patients received VRE therapy more often than noncolonized patients.Infect Control Hosp Epidemiol 2018;39:730-733.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Antimicrobial Stewardship
  • Bacteremia / drug therapy*
  • Bacteremia / epidemiology
  • Bacteremia / microbiology*
  • Cancer Care Facilities
  • Female
  • Gram-Positive Bacterial Infections / drug therapy*
  • Gram-Positive Bacterial Infections / epidemiology
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Male
  • Middle Aged
  • Regression Analysis
  • Retrospective Studies
  • Transplantation, Homologous
  • Vancomycin-Resistant Enterococci / isolation & purification*
  • Washington / epidemiology
  • Young Adult

Substances

  • Anti-Bacterial Agents