Acute gastric dilatation in a patient with lupus nephritis: An uncommon presentation of lupus mesenteric vasculitis

Saudi J Kidney Dis Transpl. 2018 Mar-Apr;29(2):429-434. doi: 10.4103/1319-2442.229279.

Abstract

Abdominal symptoms are common in patients with lupus nephritis and are often attributed to drugs or uremia per se. Lupus mesenteric vasculitis (LMV) or lupus enteritis is a rare entity reported in patients with active systemic lupus erythematosus. It usually occurs in patients with a long-standing history of lupus with high disease activity. Usually, small bowel is predominantly affected. The stomach and rectum are spared in view of significant collateral circulation. Here, we describe an 18-year-old boy who presented with nephrotic syndrome without any extrarenal features of lupus. On subsequent evaluation, he was found to have active lupus nephritis. He developed acute gastric dilatation secondary to extensive LMV. Imaging showed an extensive involvement of gastrointestinal tract from the stomach to the sigmoid colon, sparing the rectum. To the best of our knowledge, this is the first report of LMV presenting as acute gastric dilatation.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adolescent
  • Biopsy
  • Diagnosis, Differential
  • Fatal Outcome
  • Fluorescent Antibody Technique
  • Gastric Dilatation / diagnostic imaging
  • Gastric Dilatation / etiology*
  • Gastric Dilatation / therapy
  • Humans
  • Lupus Nephritis / complications*
  • Lupus Nephritis / diagnosis
  • Lupus Nephritis / therapy
  • Male
  • Mesentery / blood supply*
  • Predictive Value of Tests
  • Systemic Vasculitis / diagnostic imaging
  • Systemic Vasculitis / etiology*
  • Systemic Vasculitis / therapy
  • Tomography, X-Ray Computed