[Pyoderma gangrenosum following hematopoietic stem cell transplantation]

Ann Dermatol Venereol. 2018 Jun-Jul;145(6-7):445-450. doi: 10.1016/j.annder.2018.02.015. Epub 2018 May 7.
[Article in French]

Abstract

Background: Pyoderma gangrenosum (PG) is a rare form of neutrophilic dermatosis and is a potential complication in a number of systemic diseases. These include blood diseases, which represent 3.5% of cases, with the main forms being monoclonal gammopathy and acute myeloid leukemia.

Patients and methods: Herein we report a case of pyoderma gangrenosum in a female patient who had undergone haematopoietic stem cell allograft six months earlier as part of her treatment for acute T-cell leukemia.

Discussion: This condition forms one of the general disorders potentially associated with PG and is a dermatological disorder that can occur in marrow graft patients.

Keywords: Allogreffe de cellules souches hématopoïétiques; GVH; GVHD; Graft-versus-host disease; Hematopoietic stem cell transplantation; Pyoderma gangrenosum; Réaction du greffon contre l’hôte.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Postoperative Complications / etiology*
  • Pyoderma Gangrenosum / etiology*
  • Young Adult